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Image Search Results
Journal: Journal of Cancer
Article Title: SKA2-mediated transcriptional downregulation of the key enzyme of CoQ 10 biosynthesis PDSS2 in lung cancer cells
doi: 10.7150/jca.79058
Figure Lengend Snippet: Functional implication of SKA2-PDSS2 axis in lung cancer. ( a ) Boxplots of PDSS2 expression in TCGA lung cancer dataset. ( b ) PDSS2 expression levels were analyzed with qRT-PCR using OriGene TissueScan lung cancer panels (HLRT103). The stages were divided into I, II, III, and IV. “N” means normal. The wide bars denote the mean levels of PDSS2, while the narrow ones represent standard deviation away from the mean. ( c ) Survival analysis in relation to SKA2 and PDSS2 expression in lung cancer. Kaplan-Meier plot of overall survival of lung cancer patients in the GSE13213 dataset, the p-values were calculated using Log-rank test. ( d ) PDSS2 abrogates SKA2-promoted lung cancer cells growth. Cells were transfected with indicated plasmids and cell growth was continuously monitored by JULI Stage Real-time Cell History Recorder. ( e, f ) Cell motility analysis. Cell motility was also captured every 15 minutes for 12 hours by the aforementioned instrument. Motile trajectory, mean total migration distances and mean migration speeds are presented.
Article Snippet:
Techniques: Functional Assay, Expressing, Quantitative RT-PCR, Standard Deviation, Transfection, Migration
Journal: British Journal of Cancer
Article Title: SKCG-1 : a new candidate growth regulatory gene at chromosome 11q23.2 in human sporadic Wilms tumours
doi: 10.1038/sj.bjc.6603090
Figure Lengend Snippet: Full-length cDNA sequence and deduced amino-acid sequence of SKCG-1 . The full-length SKCG-1 cDNA encodes a predicted polypeptide of 124 amino acids. The polyadenylation signal is underlined. Sequence has been submitted to the NCBI database and the assigned GenBank accession number for SKCG1 is AY662656.
Article Snippet: The expression of SKCG-1 gene among the various tissues was analysed by PCR using
Techniques: Sequencing
Journal: British Journal of Cancer
Article Title: SKCG-1 : a new candidate growth regulatory gene at chromosome 11q23.2 in human sporadic Wilms tumours
doi: 10.1038/sj.bjc.6603090
Figure Lengend Snippet: Distribution of SKCG-1 gene expression in various human tissues. Expression of SKCG-1 gene among the various tissues analysed by SKCG-1 gene-specific PCR using tissue-specific cDNA panel (OriGene Technologies). Arrow indicates the expected size (300 bp) PCR product of SKCG-1 from tissue-specific cDNA.
Article Snippet: The expression of SKCG-1 gene among the various tissues was analysed by PCR using
Techniques: Gene Expression, Expressing
Journal: British Journal of Cancer
Article Title: SKCG-1 : a new candidate growth regulatory gene at chromosome 11q23.2 in human sporadic Wilms tumours
doi: 10.1038/sj.bjc.6603090
Figure Lengend Snippet: Sequence alignment at cDNA level of SKCG-1 with a solute carrier family 14 (urea transporter) gene ( A ), and SOS2-like protein kinase mRNA ( B ).
Article Snippet: The expression of SKCG-1 gene among the various tissues was analysed by PCR using
Techniques: Sequencing